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Silvia Deaglio Selected Research

Hypoxia (Hypoxemia)

1/2021Targeting of the A2A adenosine receptor counteracts immunosuppression in vivo in a mouse model of chronic lymphocytic leukemia.
3/2020Immune Response Dysfunction in Chronic Lymphocytic Leukemia: Dissecting Molecular Mechanisms and Microenvironmental Conditions.
10/2017Macitentan, a double antagonist of endothelin receptors, efficiently impairs migration and microenvironmental survival signals in chronic lymphocytic leukemia.
11/2016Adenosine signaling mediates hypoxic responses in the chronic lymphocytic leukemia microenvironment.
1/2009Regulation of transferrin receptor 2 in human cancer cell lines.

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Silvia Deaglio Research Topics

Disease

42Neoplasms (Cancer)
05/2024 - 04/2003
33B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
10/2023 - 02/2002
8Melanoma (Melanoma, Malignant)
05/2024 - 01/2016
6Inflammation (Inflammations)
01/2022 - 03/2009
5Leukemia
12/2022 - 07/2008
5Hypoxia (Hypoxemia)
01/2021 - 01/2009
5Disease Progression
01/2018 - 04/2003
4Hematologic Neoplasms (Hematological Malignancy)
10/2023 - 01/2013
4Infections
01/2021 - 07/2008
3Breast Neoplasms (Breast Cancer)
01/2016 - 05/2002
2Lung Neoplasms (Lung Cancer)
09/2022 - 01/2019
2Reperfusion Injury
01/2022 - 01/2021
2Sepsis (Septicemia)
01/2021 - 01/2020
2Obesity
01/2021 - 01/2020
2Lymphoma (Lymphomas)
01/2018 - 08/2012
2Glioblastoma (Glioblastoma Multiforme)
09/2012 - 04/2010
2Neuroblastoma
10/2011 - 04/2005
1Necrosis
04/2024
1Hypocalcemia
03/2024
1Pathologic Processes
08/2023
1Renal Insufficiency (Renal Failure)
01/2023
1Proteinuria
01/2023
1Kidney Diseases (Kidney Disease)
01/2023
1Chronic Renal Insufficiency
01/2023
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2022
1Mesothelioma
09/2022
1Atypical Hemolytic Uremic Syndrome
01/2022
1Methylmalonic acidemia with homocystinuria
01/2022
1Methylmalonic acidemia
01/2022
1Respiratory Tract Infections (Respiratory Tract Infection)
01/2022
1Fibrosis (Cirrhosis)
01/2022
1Hyperhomocysteinemia
01/2022
1COVID-19
01/2021
1Chronic Disease (Chronic Diseases)
01/2021
1Inborn Genetic Diseases (Disease, Hereditary)
01/2021
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2021
1Skin Neoplasms (Skin Cancer)
12/2020
1Colorectal Neoplasms (Colorectal Cancer)
03/2020

Drug/Important Bio-Agent (IBA)

7EnzymesIBA
10/2022 - 06/2011
7NAD (NADH)IBA
10/2022 - 03/2009
7Adenosine (Adenocard)FDA LinkGeneric
01/2021 - 12/2011
6LigandsIBA
11/2019 - 03/2003
5Nicotinamide PhosphoribosyltransferaseIBA
10/2022 - 01/2015
4CytokinesIBA
04/2018 - 06/2012
4fludarabineIBA
06/2012 - 12/2010
3Cell-Free Nucleic AcidsIBA
04/2024 - 01/2021
3AntibodiesIBA
01/2022 - 04/2005
3Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2016
3ElementsIBA
01/2018 - 06/2008
3NucleosidesIBA
01/2016 - 01/2011
3Transferrin Receptors (Transferrin Receptor)IBA
04/2010 - 07/2007
2Proteins (Proteins, Gene)FDA Link
10/2023 - 09/2012
2Drug CombinationsIBA
10/2023 - 07/2011
2Immunoglobulin M (IgM)IBA
12/2022 - 04/2005
2Toll-Like Receptors (Toll-Like Receptor)IBA
12/2022 - 01/2020
2Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)IBA
09/2022 - 01/2019
2AsbestosIBA
09/2022 - 01/2019
2AntigensIBA
01/2022 - 01/2017
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2019 - 10/2017
2Adenosine Triphosphate (ATP)IBA
04/2018 - 01/2018
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2018 - 11/2016
2Niacinamide (Nicotinamide)FDA LinkGeneric
01/2018 - 07/2011
2Interleukin-10 (Interleukin 10)IBA
11/2016 - 02/2015
2Messenger RNA (mRNA)IBA
09/2012 - 05/2011
2Hemoglobins (Hemoglobin)IBA
06/2012 - 09/2007
2IronIBA
01/2009 - 07/2007
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
05/2024
1Mechanistic Target of Rapamycin Complex 2IBA
05/2024
1DNA (Deoxyribonucleic Acid)IBA
04/2024
1Calcium-Sensing ReceptorsIBA
03/2024
1OT-82IBA
02/2024
1selinexorIBA
10/2023
1idelalisibIBA
10/2023
1Antineoplastic Agents (Antineoplastics)IBA
10/2023
1CreatinineIBA
01/2023
1Dronabinol (THC)FDA LinkGeneric
10/2022
1Cisplatin (Platino)FDA LinkGeneric
09/2022
1Pemetrexed (MTA)FDA Link
09/2022
1Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
01/2022
1Methionine (L-Methionine)FDA Link
01/2022
1C-Reactive ProteinIBA
01/2022
1Receptor Tyrosine Kinase-like Orphan ReceptorsIBA
01/2021
1Blood Group Antigens (Blood Groups)IBA
01/2021
1Immunoconjugates (Immunoconjugate)IBA
01/2021
1HLA Antigens (Human Leukocyte Antigens)IBA
01/2021
1Cyclin-Dependent Kinase 4IBA
01/2021
1Heme (Haem)IBA
01/2021
1Purinergic P1 Receptors (Adenosine Receptor)IBA
01/2021
1Adenosine DeaminaseIBA
01/2021
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
12/2020
1Ascorbic Acid (Vitamin C)FDA LinkGeneric
03/2020
1Cetuximab (Erbitux)FDA Link
03/2020

Therapy/Procedure

21Therapeutics
05/2024 - 02/2002
3Drug Therapy (Chemotherapy)
10/2023 - 04/2003
3Organ Transplantation
01/2023 - 01/2021
3Transplantation
01/2023 - 01/2022
2Liver Transplantation
08/2023 - 01/2022
1AT protocol
01/2022
1Precision Medicine
01/2022
1Immunotherapy
01/2021